Comparative quantitation for the protein content of diphtheria and tetanus toxoids by DC protein assay and Kjeldahl method.

A Modified Method for the Concentration and Purification of Diphtheria and Tetanus Toxoids

Humoral immune response to Diphtheria and Tetanus toxoids by intranasal administration

  The immunogenicity of ten different formulations of intranasal diphtheria and tetanus vaccines which containing different absorption enhancers, adjuvants and other excipients were determined in guinea pigs by the serum neutralization (SN) method. From these ten formulations, it was selected four formulations which gave significant immunogenicity in guinea pigs. In order to design the "final f...

Oral Immunization against Diphtheria and Tetanus Infections by Fluid Dphtheria and Tetanus Toxoids

Incorporation of T-cell epitopes from tetanus and diphtheria toxoids into in-silico-designed hypoallergenic vaccine may enhance the protective immune response against allergens

Objective(s): New generation of allergy vaccines is capable of promoting the development of protective IgG and blocking the functionality of allergen-specific IgE. We incorporated universal and powerful T-cell epitopes from tetanus and diphtheria toxoids (TD epitope) into recombinant Che a 2, the well-known allergic profilin of Chenopodium album, to determine its immun...

Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children

Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured DTwP vaccine administered to preschool children in a number of health centers of Tehran in 2...